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About Janus Henderson Investors

Janus Henderson Investors is a venture capital firm founded in 1934. It is primarily based out of London, United Kingdom. As of May 2025, Janus Henderson Investors is an active investor, having invested in 146 companies, with 8 new investments in the last 12 months. It primarily invests in Series B round in United States based startups. Its investments are spread across a wide range of sectors from Life Sciences to High Tech and Enterprise Applications. Most recently it led the $80M Post IPO round of LEXEO Therapeutics along with Frazier Life Sciences. This round also saw participation from Ally Bridge Group and other investors.
Overall, Janus Henderson Investors portfolio has seen 5 unicorns, 67 IPOs and 29 acquisitions including key companies like Workday, Okta and Lyft. A lot of funds co-invest with Janus Henderson Investors, with names like Logos sharing a substantial percentage of its portfolio.
Janus Henderson Investors has team of 100 people including 24 partners.
Key Metrics
Portfolio Count
Portfolio Sectors
Portfolio Locations
Rounds of Entry
Series B, Series C & 10 more
Portfolio Acquisitions
Portfolio Unicorns
Deals in last 12 months

Janus Henderson Investors' List of Top Investments

Janus Henderson Investors has a portfolio of 146 companies, including 5 unicorns. Their most notable investments are in Simba and Element Biosciences.Their portfolio spans across United States, United Kingdom, India and 9 more locations. They have invested in Life Sciences, High Tech, Enterprise Applications and 18 other sectors, across stages such as Series B, Series C  and 10 more. Here is the list of top investments by Janus Henderson Investors:
Cloud-based financial management, EPM, and HR software provider for enterprises. It uses AI and ML algorithms to predict work and automate tasks, manage employees, and more. The product offerings include HCM, a human capital management solution with features such as reporting and analysis, employee engagement, workforce planning, scheduling, recruiting, onboarding, benefits, etc. It also provides solutions such as financial management, business planning, analytics, professional services automation, and more. It serves multiple industry verticals including communications, energy an resources, financial services, government, healthcare, higher education, hospitality, and others.

Key facts about Workday

  • Founded Year: 2005
  • Location: Pleasanton (United States)
  • Annual Revenue: €8.92M as on Jan 31, 2023
  • Stage: Public
  • Total Funding till date: $352M
  • Employee Count: 11,805 as on Dec 31, 2022
  • Investors: InterWest Partners, Open X Innovations and 10 Others
  • Latest Funding Round: Post IPO, May 15, 2013, $45.7M
  • Highlight: Public

2. Okta

Cloud-based multi-factor authentication solutions for businesses. It is a cloud-based identity and access management platform that enables authentication and authorization for employees, customers, and partners across various applications and services.It enables enterprises to manage user identities, authenticate and authorize user access, and enforce security policies across a wide variety of apps and devices.

Key facts about Okta

  • Founded Year: 2009
  • Location: San Francisco (United States)
  • Annual Revenue: $2.26B as on Jan 31, 2024
  • Stage: Public
  • Total Funding till date: $228M
  • Employee Count: 5,908 as on Jan 31, 2024
  • Investors: Vulcan Capital, Glynn Capital and 13 Others
  • Latest Funding Round: Post IPO, Feb 21, 2018, $300M
  • Highlight: Public

3. Lyft

App-based ride-hailing aggregator. Their platform enables users to book rides by providing various details like location, passenger details, and more. It offers various services like taxi-hailing, self-driven vehicle rentals, and more. It offers features like real-time tracking, variant payments, insured rides, ride-based rewards, and more. Also, it offers industry-specific ride-hailing and concierge services for healthcare, business travel, higher education, and more. Their mobile app is available for both Android and iOS devices.

Key facts about Lyft

  • Founded Year: 2007
  • Location: San Francisco (United States)
  • Stage: Public
  • Total Funding till date: $5.02B
  • Employee Count: 4,419 as on Dec 31, 2022
  • Investors: HTIF, Kaplan Group Investments and 160 Others
  • Latest Funding Round: Series I, Aug 06, 2018
  • Highlight: Public
Online platform that provides credit score data for businesses and individuals. It provides a platform for gathering and aggregating data about customers and enterprises. It also provides credit monitoring, identity theft prevention, scanning of social security numbers, account administration, digital credit marketing, client targeting, and scoring tools. It employs artificial intelligence and automation technology to manage customer and staff experiences, enhance credit decisioning, and prevent fraud. It also offers services for credit cards, personal loans, and insurance estimates.

Key facts about Equifax

  • Founded Year: 1899
  • Location: Atlanta (United States)
  • Annual Revenue: $5.68B as on Dec 31, 2024
  • Stage: Public
  • Employee Count: 1,691 as on Aug 31, 2024
  • Investors: First Analysis, Capital Group and 44 Others
  • Latest Funding Round: Conventional Debt, May 2018, $1B
  • Highlight: Public

Key facts about Catholic Syrian Bank

  • Founded Year: 1920
  • Location: Thrissur (India)
  • Annual Revenue: ₹3,510Cr as on Mar 31, 2024
  • Stage: Public
  • Total Funding till date: $16M
  • Employee Count: 7,863 as on Mar 31, 2024
  • Investors: Janus Henderson Investors, Fairbridge Capital and 7 Others
  • Latest Funding Round: PE, 2015
  • Highlight: Public
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Janus Henderson Investors' Investments by Stage

Janus Henderson Investors has made 44 investments in Series B stage with an average round size of $123M, 26 investments in Series C stage with an average round size of $112M and 19 investments in Series A stage with an average round size of $98.6M.
Here are Janus Henderson Investors' investments by stage:
Note: We have considered here, only first round of investments
Breakdown of Janus Henderson Investors' investments by stage of entry - domiterapia.comSeries B (44)Series C (26)
Stage of entry
No. of Investments
Series B
44
Series C
26
Series A
19
Series D
17
Post IPO
10
Others
19

Janus Henderson Investors' Investments by Sector

Janus Henderson Investors has a diverse portfolio, with companies operating in the Life Sciences, High Tech, Enterprise Applications, Healthcare and Sustainability Tech. Notably, it has invested in 119 Tech companies, 117 Enterprise (B2B) companies, 12 Software companies and at least 11 companies focusing on Consumer (B2C).
Here are Janus Henderson Investors' investments by sector:
Note: We have considered here, only first round of investments
Breakdown of Janus Henderson Investors' investments by sectors - domiterapia.comLife Sciences (107)High Tech (23)
Sector
No. of Investments
Life Sciences
107
High Tech
23
Enterprise Applications
9
Healthcare
8
Sustainability Tech
7
Others
42

Janus Henderson Investors' Investments by Geography

Janus Henderson Investors has made most investments in United States (112), followed by United Kingdom where it has made 10 investments.
Here are Janus Henderson Investors' investments by geography:
Note: We have considered here, only first round of investments
Breakdown of Janus Henderson Investors' investments by countries - domiterapia.comUnited States (112)United Kingdom (10)
Country
No. of Investments
United States
112
United Kingdom
10
Canada
5
India
3
Denmark
2
Others
6

Janus Henderson Investors' recent investments

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Janus Henderson Investors has made 3 investments in 2025 so far. LEXEO Therapeutics and HeartFlow are the latest among them.
Here are the most recent investments by Janus Henderson Investors:
Date
Company
Location
Round Details
Round Amount
Co-Investors
May 27, 2025
United States
Post IPO
$80M
Mar 27, 2025
United States
Series F
$98.4M
Mar 06, 2025
United States
Series B
$110M
Medicxi [+6]
Dec 19, 2024
United Kingdom
Series A
$140M
Orbimed [+7]
Dec 04, 2024
United States
Series D
$115M
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Unicorns in Janus Henderson Investors' Portfolio

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Janus Henderson Investors has 5 unicorns in its portfolio - IntelyCare, Loadsmart, Freenome and others. The most recent unicorn in their portfolio is IntelyCare. It became a unicorn in 2022.
Here is a list of unicorns in Janus Henderson Investors' portfolio:
Tracxn Score
Company
Short Description
Founded year
Sector
Location
Company Stage
First Investment/ Acquisition Details
58
Online contract workforce recruitment platform for nurses
2016
Quincy
Series C
xocipco
66
Online marketplace for booking trucking services
2014
New York City
Series D
yibodpk
67
Provider of a deep learning platform for detecting circulating cancer-related markers
2014
San Francisco
Series E
eii{mpe
67
Provider of end-to-end intelligent transport solutions to public transport operators
2012
New York City
Series G
agwhdrs
53
Provides cardiovascular diagnostic support using analytics
2007
Redwood City
Series F
erkmjve

IPOs and Publicly Listed companies in Janus Henderson Investors' Portfolio

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67 of Janus Henderson Investors' portfolio companies have become public. Maze Therapeutics got listed on the National Association of Securities Dealers Automated Quotations (NASDAQ), in Jan 2025 at marketcap of $700M and Metsera got listed on the National Association of Securities Dealers Automated Quotations (NASDAQ) at marketcap of $1.85B.
Here are Janus Henderson Investors' portfolio companies that went public:
Company
IPO Date
First Invested on
First Round of Investment
Round Size
Jan 31, 2025
Dec 04, 2024
Series D
$115M
Jan 31, 2025
Nov 12, 2024
Series B
$215M
Sep 13, 2024
Mar 06, 2023
Series B
$108M
Jul 19, 2024
Feb 22, 2021
Series B
$120M
Jan 25, 2024
Aug 01, 2023
Series E
$105M

Acquired companies in Janus Henderson Investors' Portfolio

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29 companies from Janus Henderson Investors' portfolio have been acquired. The most recent acquisition were Verve in Jun 2025 by Lilly.
Here are Janus Henderson Investors' portfolio companies that got acquired most recently:
Company
Acquisition Date
First Invested on
First Round of Investment
Round Size
Jun 17, 2025
Jan 19, 2021
Series B
$94M
Apr 03, 2024
Feb 13, 2024
Series B
$112M
Feb 16, 2024
Jul 21, 2020
Series C
$98M
Dec 26, 2023
Aug 07, 2023
Post IPO
Undisclosed
Dec 14, 2023
Sep 03, 2020
Series B
$72.6M

Team profile of Janus Henderson Investors

Janus Henderson Investors has a team of 100 members including 24 Partners and 66 Principals located in United Kingdom, United States and 8 more locations. Janus Henderson Investors' team does not sit on the board of any company as of now.
Here is a list of top team members in Janus Henderson Investors:
Name
Designation
Location
Board Memberships
Contact details
Partner
-
-
-
Partner
London
-
-
Partner
London
-
Partner
Denver
-
-
Partner
Denver
-
-
Partner
Twickenham
-
-
Partner
Taipei
-
-
Partner
Denver
-
-
Partner
Phoenix
-
-
Partner
Ireland
-
-
Partner
New York City
-
-
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Co-investors of Janus Henderson Investors

Over the past 25 years, 987 investors have co-invested in Janus Henderson Investors's portfolio companies.

  • Invested before Janus Henderson InvestorsHHS, RA Capital Management and 410 others have invested in rounds before Janus Henderson Investors. There are 11 companies where HHS has invested before Janus Henderson Investors and 9 companies where RA Capital Management has invested before Janus Henderson Investors.
  • Top Co-investors of Janus Henderson Investors361 investors entered a company along with Janus Henderson Investors. These include investors like Logos (36 companies).
  • Invested after Janus Henderson InvestorsA total of 214 investors have invested in Janus Henderson Investors's portfolio after their investments. Top Investors include Fidelity Investments (5 companies), RA Capital Management (5 companies) and Bain Capital Life Sciences (4 companies).
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FAQ's about Janus Henderson Investors

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